They told the Ghana News Agency (GNA) in an interview at Sunyani that they could not accommodate the bad odour which emanated from the abattoir.
According to the residents, they had made several complaints to the Sunyani Municipal Assembly to close down the abattoir but no positive action had been taken.
When the GNA visited the abattoir, it was in a dilapidated condition and posed a threat to the well-being of the workers.
The workers had to slaughter and prepare the carcass on the bare floor because there were no hooks to hang them on.
One of them who spoke on condition of anonymity explained that it was built in 1972 but since then the abattoir had not seen any major rehabilitation.
Because we do not wear any protective gear, some of us get sick regularly since we are forced to breathe the bad odour at the facility, he added.
Mr Simon Opoku, Sunyani Municipal Environmental Officer confirmed the story but added that the Assembly was making efforts to rectify the situation.