This is being done in close collaboration with the Ghana Private Road Transport Union (GPRTU) and other driver associations.
It involves the holding of education durbars and forums at the lorry terminals and in the various communities.
Deputy Superintendent of Police (DSP) Samuel Sandow Latebu, the District Commander, who is leading the campaign, said they were targeting not only drivers and other motorists, but pedestrians and travellers.
They would reach out to all stakeholders and help everybody to take responsibility and stop the carnage.
Addressing one of such forums at Juaso, he said the recklessness and impunity could no longer be accepted.
He warned that those who flouted the laws would be arrested and brought to justice to restore sanity.
The District Commander urged the leadership of the various driver associations to aid their members to appreciate the need to value life and to be more careful on the road.
Mr Atta Mensah, the Deputy District Coordinating Director, said the DISEC would go to every length to reverse the disturbing trend of road crashes in the area.
Mr Emmanuel Yeboah, a driver, invited his colleagues to heed to safety education.