The clash, billed for the Baba Yara Sports Stadium in Kumasi, will have nothing at stake but pride as the curtain goes down on the qualifiers for the two competitions.
Mali and Benin will hope to either maintain or improve on their standings.
The Stars lost their unbeaten run in the penultimate clash against Les Ecuriels of Benin last month in Cotonou and are banking heavily on a massive victory to reclaim the love and support of their huge following.
The Stars beat the Eagles 2-0 in Bamako with goals from new kid on the bloc, Kwadwo Asamoah and Matthew Amoah, a result which set the tone for their qualification to their second successive Mundial.
The Serb has handed expected call-ups to seven players of the victorious Black Satellites squad at the just ended FIFA U-20 World Cup in Egypt.
The six will complement the efforts of 'old horses' Captain Stephen Appiah, Michael Essien, Asamoah Gyan and John Paintsil among others for a resounding victory to climax their qualifying series.
The Stars launched their campaign with a 3-0 win over the Greens of Libya last year at the same venue.
GNA
